Tretinoin Nanogel 0.025% Versus Conventional Gel 0.025% in Patients with Acne Vulgaris: A Randomized, Active Controlled, Multicentre, Parallel Group, Phase IV Clinical Trial
Background: Conventional topical tretinoin formulation is often associated with local adverse events.Nanogel formulation of tretinoin has good physical stability and enables good penetration of tretinoin into the pilo-sebaceous glands.Aim: The present study was conducted to assess the efficacy and safety of a nanogel formulation of tretinoin as com